发表论文
2020年
[1] Yunfei Wang, Zhengrong Li, Boxue Liu, Rumeng Wu, Haifeng Gong, Zhanhai Su, Shoude Zhang*. Isoborneol Attenuates Low-Density LipoproteinAccumulation and Foam Cell Formation in Macrophages. Drug Design, Development and Therapy 2020:14 167–173
2022年
[1] Yongchun Huang, Jie Zhang, Pengxiang Zhao, Yufeng Ma, Qiangqiang Jia, Shoude Zhang. Study on the mechanism of cholic acid derivatives in Traditional Chinese Medicine based on the regulation of gene expression. Journal of Traditional Chinese Medical Sciences. 2023. 10: 35-41. DOI: https://doi.org/10.1016/j.jtcms.2022.11.001
[2] Rumeng Wu, Qiangqiang Jia, Xiuzhang Li, Yufeng Ma, Jie Zhang, Yuling Li, Shoude Zhang*. Preparation of the sphingolipid fraction from mycelia of Cordyceps sinensis and its immunosuppressive activity. Journal of Ethnopharmacology.2022. 291:115-126
2023年
[1] Weirong Song, Jie Zhang, Pengxiang Zhao, Yongchun Huang, Shoude Zhang. A new monoterpene alkaloid from Incarvillea Sinensis with migration inhibitory activity on cancer cell. Chemistry & Biodiversity. 2023, 20: e202201203. DOI: https://doi.org/10.1002/cbdv.202201203.
[2] Yufeng Ma, Fengsen Zhang, Yijing Zhong, Yongchun Huang, Yixizhuoma, Qiangqiang Jia, Shoude Zhang. .A label-free LC/MS-based enzymatic activity assay for the detection of PDE5A inhibitors. Frontiers in Chemistry. 2023. 13(11):109702
2024年
[1] Pengxiang Zhao, Jie Zhang, Weirong Song, Danshi Qi, Yongchun Huang. Shoude Zhang. Incarvine C and its analogues inhibit the formation of cell cytoskeleton by targeting Rac1. Bioorganic Chemistry. 2024, 149: 107512. DOI: https://doi.org/10.1016/j.bioorg.2024.107512
[2] Changting He, Yuling Zhao, Yongchun Huang, Yudong Su, Shoude Zhang. Analysis of the mechanism of Zangjiangzhi capsule in the treatment of hyperlipidemia based on its ingredients identified by UHPLC-Q-Exactive Orbitrap MS. Journal of Traditional Chinese Medical Sciences. 2024, 12(1): 44-55. DOI: https://doi.org/10.1016/j.jtcms.2024.11.003.
2025年
[1] Yudong Su, et al. Procyanidin Improves Erectile Function in Rats by Inhibiting PDE5A Activity. Drug Design, Development and Therapy. 2025:19 3351–3361. DOI:10.2147/DDDT.S514209
[2] Danshi Qi, et al. Four Novel ROCK1 Inhibitors Suppressing Cytoskeleton and Movement in Breast Cancer Cells. Chemistry & Biodiversity. 2025. e202500258. DOI:10.1002/cbdv.202500258
[3] Jinman Shui, Shaohua Yang, Yuling Zhao, Danshi Qi, Yudong Su, Jie Bai, Shoude Zhang. Advances and prospects of targeting research for polysaccharide based drugs: A review. Carbohydrate Polymer Technologies and Applications. 2025. 9:100735. DOI: 10.1016/j.carpta.2025.100735
[4] Yongchun Huang, Jie Bai, Jinman Shui, Zhanhai Su, Chengzhu Cao, Haiyan Wang, Qiong Wu, Shoude Zhang. Simultaneous determination of the monosaccharide types and their absolute configurations in polysaccharides based on UPLC-MS/MS. International Journal of Biological Macromolecules. 2025, 295:139647. DOI: https://doi.org/10.1016/j.ijbiomac.2025.139647
出版专著
[1] 《蛋白质晶体学与药物发现》化学工业出版社2025.03
主持与完成项目
（1）2014.1-2016.12“倍半萜内酯类化合物Britain抗自身免疫性心肌炎的作用机制研究” 国家自然科学青年基金项目，项目编号：81302651，经费：25万
（2）2018.1-2020.12“藏波罗花中生物碱类成分的抗肿瘤活性及其作用机理研究”，青海省自然基金青年项目，编号：2018-ZJ-948Q 经费：20万
（3）2021.1-2024.12 “角蒿中哌啶类单萜生物碱靶向调控肌动蛋白细胞骨架组装抗肿瘤的作用机制和构效关系研究”，国家自然科学基金,地区科学基金项目，项目编号：22067016，经费：41万
（4）2021.1-2023.12“中药锁阳中PDE5抑制剂的制备工艺研究及改善性能产品的研发”，青海省重点研发与转化计划项目，项目编号：2021-QY-203, 经费：100万
（5）2023.1-2025.12"中藏药靶向活性成分的筛选方法研究，青海省杰出青年基金项目 2023-ZJ-964J，经费：60万（6）2025.1-2028.12 靶向活性位点含有半胱氨酸靶标蛋白的药物筛选方法研究, 国家自然科学基金,地区科学基金项目，项目编号：22467019，经费：32.8万
获批专利
（1）一种靶向荧光探针分子及其合成方法和应用，第一发明人 专利号：ZL 202310191274.2
（2）锁阳精多糖、锁阳多糖化合物及制备方法和应用
专利号: ZL202310574630.9
登记成果
（1）藏波罗花中生物碱类成分的抗肿瘤活性极其作用机理研究
